Find out if you’re eligible for the Skin Renewal Program

What is your main reason for wanting to improve your skin?

Hero photography — TK

Measure your Skin Age. Then reverse it.

  • Advanced skin renewal medications shipped to your door
  • Easy at-home DNA biomarker testing
  • A personalized plan and custom-formulated supplements for accelerated results
See if you’re eligible
Collagen breakdownElevated
UV responseReduced
Glycation clearanceReduced
Inflammation responseTypical
Antioxidant defenseTypical
DNA repair capacityReduced
PigmentationTypical
Barrier repairTypical
Sebum driveElevated
Under-eye pigmentTypical

Developed with research from the world’s leading longevity dermatology experts

Everything it takes to reverse your Skin Age

No more guessing what works — just the most powerful, personalized way to reverse your Skin Age

The medical protocol

Advanced medications that renew skin at the cellular level.

Complete Skin Intelligence DNA Test

The test that finally explains what’s aging your skin.

Personalized skin renewal plan and supplements

Personalized to your DNA to accelerate your progress.

See if you’re eligible
Rx Protocol DNA Test Plan & Supplements See if you’re eligible
Rx Protocol

This is medicine, not maintenance.

Don’t just improve the appearance of skin. Renew it structurally by reversing the cellular causes of aging.

Protocol imagery — TK
Clears senescent cells

Clears out the aged cells that accumulate and inflame the tissue around them

Targets
WrinklesFirmness
Repairs photodamage

Repairs the UV damage stored in your skin from years of exposure

Targets
Dark spotsHyperpigmentationWrinkles
Blocks glycation

Blocks the glucose that bonds to and stiffens collagen — a reaction that accelerates with age, even if your diet is healthy

Targets
FirmnessWrinkles
Neutralizes oxidative stress

Strengthens your skin’s defenses against free-radical damage

Targets
Surface roughnessDark spots
Calms chronic inflammation

Quiets the low-grade inflammation degrading collagen in the background

Targets
RednessHyperpigmentation
Restores NAD+

Replenishes the coenzyme your skin cells use for repair

Targets
Dark circlesSurface roughness
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DNA Test

Biomarkers That Matter

The Oona DNA test is an easy, at-home test that gives you clear, actionable insights on what’s working for your skin and what needs attention.

DNA kit photography — TK
  • Convenient at-home test kit
  • Completely painless — saliva, not blood
  • Actionable skin insights

We read 48 genetic markers handpicked by our clinical team to show what’s driving your skin’s aging — and what to do about it.

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Skin Aging Biology

Perceived facial agePhotodamage susceptibilityWrinkle riskCollagen breakdownBarrier repairSebum driveUnder-eye pigmentDNA repair capacityEyelid laxityPigmentation

Sun & Pollution

UV sensitivityPollution response

Redness & Flushing

Immune-mediated rednessInflammatory toneHistamine clearance

Medication Response

Used by your physician to tailor your prescription.

Medication metabolismMedication responseSkin barrier strengthPost-inflammatory pigmentation

Diet & Nutrients

Lactose toleranceCeliac riskGlycation clearanceB12 absorptionVitamin C transportOmega-3 conversionVitamin A conversionIron handlingAntioxidant enzymes

Sleep, Stress & Training

Caffeine clearanceCaffeine sensitivityAlcohol clearanceChronotypeCortisol responseTraining response
Reviewed by board-certified physicians
Encrypted end to end. You control your data.
Analyzed in CLIA-certified U.S. labs
Plan & Supplements

Accelerate your results with a personalized plan and supplements tailored to your DNA.

Your plan in your pocket

Oona turns your DNA test into a daily companion: your results, your superfoods, your formula, and your plan, in one place.

Step 1 of 4Health
Where your skin is aging fastest.
Your DNA results on the pathways that personalize your plan.
Collagen breakdownMMP1 · TIMP1 · COL1A1
SlowTypicalFast
Your skin breaks collagen down faster than it rebuilds.
DNA repair capacityXPC · ERCC2
StrongTypicalSlow
Your cells repair sun damage slowly, so the same exposure costs you more.
Glycation clearanceGLO1 · AGER · TCF7L2
LowTypicalHigh
You clear sugar-protein bonds at the usual rate; your scan still reads elevated.
Win big with these superfoods.
Chosen from your DNA results and your scan.
Start hereWild salmon
Omega-3s for your high inflammation response.
GlycationLeafy greens
Folate for your reduced activation; low glycemic load.
AntioxidantBlueberries
Anthocyanins for your weak antioxidant defense.
CollagenBone broth
Glycine and proline for fast collagen breakdown.
What eating well can't do.
Your formula picks up where food can't.
Your formula · 5 ingredients · made for you
Ingredient
5-MTHF
800 mcg
Eating it
≈ 11 cups spinach
+6
active folate; folic acid converts poorly with your MTHFR result
Ingredient
Selenium
100 mcg
Eating it
≈ 2 Brazil nuts
feeds the GPX1 enzyme your result runs low on
Ingredient
CoQ10
200 mg
Eating it
≈ 2 kg sardines
the daily amount in two kilos of oily fish
Ingredient
Omega-3 (EPA)
1,000 mg
Eating it
≈ 3 salmon fillets
chosen for your inflammation-response result
Ingredient
Glycine · proline
2 g
Not in food
Not on any plate
collagen precursors; not practical from food at this dose
Your 26-week plan to reverse 3 years of skin aging.
Focus, medications, superfoods, and formula, working together.
FocusUndereye and eye-corner wrinkles
StartYour Rx cream, nightly
AvoidCaffeine after 2 pm
Boost5-MTHF, selenium, CoQ10, omega-3
Week 1
Take your test. Start your routine.
DNA test at home, SPF 50 every morning, caffeine cutoff at 2 pm.
Week 2
Your results arrive.
Your physician sets your doses. Your formula goes into production.
Week 3
Start your medications.
Everything arrives in one box.
Weeks 4–8
Hold the routine.
Texture changes first. Your week-8 scan shows where you are.

Unique formulas based on your results

Your test results guide your personalized supplement formula, designed to support specific biological needs—so you can make faster progress toward reversing your Skin Age.*

Maya’s Formula
Here’s what’s in it.
Cellular renewal

Fisetin, quercetin, apigenin

UV resilience

Astaxanthin, polypodium leucotomos, lycopene, vitamin E

Glycation defense

Carnosine, benfotiamine, alpha-lipoic acid, taurine

NAD+ support

TMG, riboflavin, glycine

You deserve ingredients held to an uncompromising standard.

  • Evidence-based. Every ingredient is supported by peer-reviewed research — read the exact studies behind your formula.
  • Intentionally sourced. Every nutrient is chosen for its purity, stability, and absorption.
  • Clean by default. Vegetarian, non-GMO. No synthetic fillers, no artificial colors, no dubious additives. Ever.
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What makes Oona different?

Your program is engineered to treat all six mechanisms of skin aging.

TretinoinVitamin C
Cellular senescence
Photodamage
Glycation
Oxidative stress
Chronic inflammation~
NAD+ depletion
See if you’re eligible

“Science is showing that while chronological aging is inevitable, biological aging is malleable. There’s a part of it that you can fight, and we are getting closer and closer to winning that fight.”

Dr. Eric VerdinPresident and CEO, Buck Institute for Research on Aging

Here’s how it works

Quiz screen — TK
Take a brief intake survey.

Share your skin history and goals to see if the Oona program is right for you.

Kit imagery — TK
Receive your DNA testing kit.

Your kit arrives in 3–5 business days. The saliva test takes minutes — return it in the prepaid mailer to our CLIA-certified lab.

Results screen — TK
Get your results and prescription.

Your physician reviews your results and sets your dosing schedule. Your supplement formula is made from your results.

Box imagery — TK
Receive your program.

Your medications, supplements, and plan arrive in one box.

Care screen — TK
Ongoing care and support

Your medication dosing schedule will continue to adapt to your progress, supported by your clinical team.

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★★★★★
"I get Botox every four months and I'm not giving that up. What's different is my skin between appointments. It's firmer and brighter, and my results now stretch closer to six."
Lauren K., 34 · Miami
★★★★★
"After years of miracle products that did nothing, I didn't trust anyone's promises anymore. Oona started by finding out what was actually going on with my skin. Four months in, the texture around my eyes is smoother and my cheeks are firmer, and I know exactly why."
Claire W., 38 · Orlando
★★★★★
"Every esthetician had a theory about my dark spots. My DNA test showed my skin clears sun damage slowly, and the plan changed around that. The spots I'd had for a decade are finally fading."
Emily H., 41 · Tampa

Frequently asked questions

What kind of medications will I get?

Advanced injectable, oral, and topical longevity medications that treat the cellular causes of skin aging. Your physician selects and doses your protocol from your assessment, and you’ll see your exact medications before you commit to anything.

Do I need a prescription?

Yes, your treatment requires a prescription — and the program includes it. Oona physicians, all licensed in the United States, will conduct a thorough review of your health profile to assess your suitability. Upon approval, they write your prescription, and a licensed US pharmacy compounds your treatment.

Is it safe to take these with my current medications?

Your intake covers your medical history and current medications, and your physician reviews everything before prescribing. If the protocol isn’t appropriate for you, you’ll receive a full refund.

What side effects should I expect?

Some side effects are common when starting any new medication, and they usually fade as your body adjusts. Your physician will start you on conservative doses based on your assessment and DNA results. Your care team is standing by to answer any questions and can make sure your protocol gets adjusted as needed.

How is my treatment monitored over time?

Your physician reviews your progress at every scan and follow-up and adjusts your doses as your skin responds. Prescriptions renew only after physician review — never automatically.

How accurate are my DNA results?

All samples are analyzed in a CLIA-certified U.S. lab, where your skin’s aging biology is genotyped across 650K+ genetic markers.

Are my personalized supplements made unique to me?

Yes. Your personalized supplements are crafted specifically for your unique needs, based on your DNA test results. Every single order is 100% unique, built from your results and clinical research to select the nutrients that will benefit your body the most.

What ingredient types are included in my personalized supplements?

Your personalized supplements include your very own combination of vitamins, minerals, food extracts, amino acids, and herbs. The typical daily pack contains 20+ ingredients, but yours will depend on your test results.

Once I get my test results, when do I get my supplements?

After your results are released, processing for your personalized supplements begins — there’s no action you need to take. They arrive with your next order.

Is this covered by insurance?

Because our treatments are considered off-label use of FDA-approved medications, Oona cannot bill insurance directly. However, you can contact your insurance provider to see if you can file for reimbursement. We’re happy to provide the necessary paperwork upon request — just reach out to concierge@withoona.com.

Do I have control over my genetic information?

Absolutely. You control how your genetic information is used, shared, and when it is deleted.

Is my DNA data secure?

Yes. We use robust data security measures to safeguard your genetic information. Your DNA sample and genetic information are secure with Oona and our CLIA-certified laboratory partner.

Can I delete my DNA from your system?

Yes. Your DNA test results are stored in a secured database. Your DNA sample is destroyed after testing and quality control checks, and you can ask us to delete your data from our systems at any time.

Will my DNA be used for research?

No. We will not use your genetic information for research.

Reverse your Skin Age. Start today.

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See if you’re eligible